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Inhibition of c-Kit, VEGFR-2 (KDR), and ABCG2 by analogues of OSI-930
(2011)
The quinoline domain of OSI-930, a dual inhibitor of receptor tyrosine kinases (RTKs) c-Kit and KDR, was modified in an effort to further understand the SAR of OSI-930, and the binding site characteristics of c-Kit and ...