Browsing Faculty of Arts & Social Sciences (FoA&SS / FoL / FBM) by Author "Farquhar, C"

Now showing items 1-7 of 7

    • Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. 

      Baeten, JM; Donnell, D; Ndase, P; Mugo, NR; Campbell, JD; Wangisi, J; Tappero, JW; Bukusi, EA; Cohen, CR; Katabira, E; Ronald, A; Tumwesigye, E; Were, E; Fife, KH; Kiarie, J; Farquhar, C; John-Stewart, G; Kakia, A; Odoyo, J; Mucunguzi, A; Nakku-Joloba, E; Twesigye, R; Ngure, K; Apaka, C; Tamooh, H; Gabona, F; Mujugira, A; Panteleeff, D; Thomas, KK; Kidoguchi, L; Krows M, Revall J; Morrison S, Haugen H; Emmanuel-Ogier, M; Ondrejcek L, Frenkel L, Hendrix C Coombs RW,; Bumpus NN, Haberer JE, Stevens WS Bangsberg D,; Lingappa JR, Celum C (Global Health, University of Washington, Seattle, WA 98104, USA, 2012)
      BACKGROUND: Antiretroviral preexposure prophylaxis is a promising approach for preventing human immunodeficiency virus type 1 (HIV-1) infection in heterosexual populations. METHODS: We conducted a randomized trial ...

    • Cervicovaginal HIV-1-neutralizing immunoglobulin A detected among HIV-1-exposed seronegative female partners in HIV-1-discordant couples. 

      Choi, RY; Levinson, P; Guthrie, BL; Lohman-Payne, B; Bosire, R; Liu, AY; Hirbod, T; Kiarie, J; Overbaugh, J; John-Stewart, G; Broliden, K; Farquhar, C (Medicine, University of Washington, Seattle, WA 98104, USA., 2012)
      Cervicovaginal HIV-1-neutralizing immunoglobulin A (IgA) was associated with reduced HIV-1 acquisition in a cohort of commercial sex workers. We aimed to define the prevalence and correlates of HIV-1-neutralizing IgA from ...

    • Delayed initiation of antiretroviral therapy among HIV-discordant couples in Kenya. 

      Kahn, TR; Desmond, M; Rao, D; Marx, GE; Guthrie, BL; Bosire, R; Choi, RY; Kiarie, JN; Farquhar, C (University of Washington School of Medicine, Seattle, WA, USA, 2013)
      Timely initiation of antiretroviral therapy (ART) is particularly important for HIV-discordant couples because viral suppression greatly reduces the risk of transmission to the uninfected partner. To identify issues and ...

    • HIV-1-specific enzyme-linked immunosorbent spot assay responses in HIV-1-exposed uninfected partners in discordant relationships compared to those in low-risk controls. 

      Guthrie, BL; Lohman-Payne, B; Liu, AY; Bosire, R; Nuvor, SV; Choi, RY; Mackelprang, RD; Kiarie J, N; De Rosa, SC; Richardson, BA; John-Stewart, GC; Farquhar, C (Epidemiology, University of Washington, Seattle, Washington, USA., 2013)
      A number of studies of highly exposed HIV-1-seronegative individuals (HESN) have found HIV-1-specific cellular responses. However, there is limited evidence that responses prevent infection or are linked to HIV-1 exposure. ...

    • Knowledge and acceptability of pap smears, self-sampling and HPV vaccination among adult women in Kenya. 

      Rositch, AF; Gatuguta, A; Choi, RY; Guthrie, BL; Mackelprang, RD; Bosire, R; Manyara, L; Kiarie, JN; Smith, JS; Farquhar, C (Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, 2012)
      Our study aimed to assess adult women's knowledge of human papillomavirus (HPV) and cervical cancer, and characterize their attitudes towards potential screening and prevention strategies. METHODS: Women were participants ...

    • Partner characteristics predicting HIV-1 set point in sexually acquired HIV-1 among African seroconverters. 

      Lingappa, JR; Thomas, KK; Hughes, JP; Baeten, JM; Wald, A; Farquhar, C; de Bruyn, G; Fife, KH; Campbell, MS; Kapiga, S; Mullins, JI; Celum, C; Bukusi, EA (University of Washington 325 Ninth Avenue, Box 359927 Seattle, WA 98104, USA, 2013)
      Plasma HIV-1 RNA set point is an important predictor of HIV-1 disease progression. We hypothesized that inoculum size and HIV-1 exposure prior to HIV-1 transmission may modulate set point. We evaluated predictors of set ...

    • Short communication: T cell activation in HIV-1/herpes simplex virus-2-coinfected Kenyan women receiving valacyclovir. 

      Roxby, AC; Liu, AY; Drake, AL; Kiarie, JN; Richardson, B; Lohman-Payne, BL; John-Stewart, GC; Wald, A; De Rosa, S; Farquhar, C (Medicine, University of Washington, Seattle, 2013)
      Herpes simplex virus-2 (HSV-2) suppression with acyclovir or valacyclovir reduces HIV-1 viral RNA levels; one hypothesis is that HSV-2 suppression reduces immune activation. We measured T cell immune activation markers ...