| dc.contributor.author | Gopalan, HNB | |
| dc.contributor.author | Njagi, GDE | |
| dc.date.accessioned | 2015-08-04T12:10:55Z | |
| dc.date.available | 2015-08-04T12:10:55Z | |
| dc.date.issued | 1984 | |
| dc.identifier.citation | CYTOLOGIA Vol. 49 (1984) No. 1 P 209-214 | en_US |
| dc.identifier.uri | https://www.jstage.jst.go.jp/article/cytologia1929/49/1/49_1_209/_article | |
| dc.identifier.uri | http://hdl.handle.net/11295/89526 | |
| dc.description.abstract | The antimicrobial food additive AF-2 is mutagenic in bacteria, Neurospora, yeast and Drosophila. AF-2 breaks mammalian chromsomes. We studied by Feulgen staining the types and distribution of chromosome aberrations induced by AF-2 in Vicia faba root meristems. AF-2 induces (a) mitostasis resulting in accumulation of cells in G1, S or G2 phase, (b) chromosome condensation, (c) pycnosis of the interphase nuclei and (d) anaphase bridges and micronuclei. The bridges involve all the six chromosome pairs but largely the SAT-chromosomes. Attachments are confined to secondary constrictions and chromosome tips. These effects are likely to be due to an indirect action of AF-2 on the genetic material. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | University of Nairobi | en_US |
| dc.title | AF-2 Induced Chromosome Aberrations in Vicia faba Root Meristematic Cells | en_US |
| dc.type | Article | en_US |
| dc.type.material | en | en_US |
