University of Nairobi Institutional Repository: Recent submissions
Now showing items 1-20 of 105322
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Handling missing data in a composite outcome with partially observed components: simulation study based on clustered paediatric routine data
(University of Nairobi, 2021)Composite scores are useful in providing insights and trends about complex and multidimensional quality of care processes. However, missing data in subcomponents may hinder the overall reliability of a composite measure. ... -
Dhana Ya Uchimuzi Katika Uendelezaji Wa Riwaya Ya Kimajaribio Ya Mafamba
(University of Nairobi, 2012)Tasnifu hii inahusu dhana ya uchimuzi katika uendelezaji wa riwaya ya kimajaribio au mpya ya Mafamba (2008). Ni riwaya ya kwanza ya Olali inayomulika hali ya kisiasa katika jamii yetu na harakati za wananchi za kuwang'oa ... -
A diverse collection of B cells responded to HIV infection in infant BG505.
(University of Nairobi, 2021)Increasing evidence suggests infants develop unique neutralizing antibody (nAb) responses to HIV compared to adults. Here, we dissected the nAb response of an infant whose virus is in clinical trials as a vaccine immunogen, ... -
The African Vaccine-Preventable Diseases Network: a vaccine advocacy initiative.
(University of Nairobi, 2011)Achieving high and equitable childhood immunisation coverage in Africa will not only protect children from disability and premature death, it will also boost productivity, reduce poverty and support the economic growth of ... -
Feasibility of using an Early Warning Score for preterm or low birthweight infants in a low-resource setting.
(University of Nairobi, 2020)Introduction Fifteen million babies are born prematurely, before 37 weeks gestational age, globally. More than 80% of these are in sub-Saharan Africa and Asia. 35% of all deaths in the first month of life are due to ... -
WHO next-generation partograph: revolutionary steps towards individualised labour care.
(University of Nairobi, 2021)No abstract available -
In silico structural and functional prediction of African swine fever virus protein-B263R reveals features of a TATA-binding protein
(University of Nairobi, 2018)African swine fever virus (ASFV) is the etiological agent of ASF, a fatal hemorrhagic fever that affects domestic pigs. There is currently no vaccine against ASFV, making it a significant threat to the pork industry. The ... -
Phytochemical Analysis and Establishment of Embryogenic Cell Suspension and Agrobacterium-mediated Transformation for Farmer Preferred Cultivars of West African Plantain (Musa spp.)
(University of Nairobi, 2020)Banana and plantain are among the foremost staple food crops providing food and livelihood to over 500 million people in tropical countries. Despite the importance, their production is hampered due to several biotic and ... -
Comparative in silico study of congocidine congeners as potential inhibitors of African swine fever virus
(University of Nairobi, 2019)African swine fever virus (ASFV) infection is fatal in domesticated pigs, with a mortality rate approaching 100%. This may result in economic losses and threats to food security. Currently, there are no approved vaccines ... -
Risk factors for the incursion, spread and persistence of the foot and mouth disease virus in Eastern Rwanda
(University of Nairobi, 2020)Background: Identification of risk factors is crucial in Foot-and-mouth disease (FMD) control especially in endemic countries. In Rwanda, almost all outbreaks of Foot-and-Mouth Disease Virus (FMDV) have started in Eastern ... -
The impact of child labour on boys’ and girls’ participation in Public day Secondary School Education in Kiminini Sub-County, Transnzoia County, Kenya
(University of Nairobi, 2021)The purpose of this study was to investigate the impact of child labour on boys’ and girls’ participation in public day secondary school education in Kiminini sub- county Trans-Nzoia County and establish ways of mitigating ... -
Two novel lignans derivatives and two fusicoccane diterpenoids from whole plant of Hypoestes verticillaris (L.f.) Sol. ex Roem. & Schult
(University of Nairobi, 2019)Bioassay-guided screening of Hypoestes verticillaris whole plant CH2Cl2:MeOH (1:1) extract for anti-plasmodial activity yielded four new compounds: two lignans 2, 6-dimethoxysavinin (1), 2,6-dimethoxy-(7E)-7,8-dehydrohel ... -
Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?
(University of Nairobi, 2021)Background Inflammation seems to play a major role in the pathophysiology of keloids. However, the role of cytokines in keloid pathophysiology has not been fully evaluated with only a few cytokines studied. We undertook ... -
Rapid Screening using GIBEX Screens-to-nature System of Ethnomedicinal Plants from Ngong Forest, Kenya for Potency against Infectious Diseases and Antioxidant Activities: A Qualitative Study
(University of Nairobi, 2019)Introduction: Plants from Kenyan flora are traditionally used to manage a number of ailments including; chronic and infectious disease, to bolster the body immunity and for general health protections. The current investigation ... -
Cancer and COVID-19 Experiences at African Cancer Centers: The Silver Lining.
(University of Nairobi, 2021)PURPOSE The COVID-19 pandemic significantly disrupted cancer care in Africa, further exposing major health disparities. This paper compares and contrasts the experiences of 15 clinicians in six different African cancer ... -
Athari Za Udhanaishi Katika Kichwamaji Na Nanguvu Ya Sala
(University of Nairobi, 2006)Tasnifu hii imechunguza athari za udhanaishi katika riwaya mbili ambazo ni Kichwamaji na Nguvu ya Sala. Kazi yenyewe imegawika katika sura nne. Katika sura ya kwanza tumetanguliza kwa ufupi dhana ya udhanaishi. Vilevile, ... -
Mwingiliano Wa Fasihi Na Historia Katika Utenzi Wa Nchuu Cwavo Yapo Tini Mwairara (Mtu Ni Kwao Japo Chini Mwa Irara)
(University of Nairobi, 2017)Tasnifu hii inahusu mwingiliano wa fasihi na historia katika Utenzi wa Nchuu Cwavo Yapo Tini lvfwa Irara wa Abubaker M.B. Khuchi. Kazi hii ilikuwa na maIengo mahususi matatu; kwanza, kuhakiki mchango wa historia katika ... -
Oleanolic Acid and other Compounds Isolated from Cordia africana Lam which Inhibit Vancomycin Resistant Enterococcus
(University of Nairobi, 2019)ABSTRACT Introduction: Treatment of microbial infections has become complicated due to increased resistance of microbes to the current drugs. The current study investigates crude extracts and seven compounds from root ... -
Antiplasmodial Biflavanones from the Stem Bark of Garcinia buchananii Engl.
(University of Nairobi, 2019)Introduction: Plants of the genus Garcinia are traditionally used treat a range of infectious and non-infectious diseases. Garcinia species are reported to have been shown to have a range of biological activities including ... -
Antiproliferative Properties of Labdane Diterpenoids from Croton sylvaticus Hochst against Drug Sensitive and Resistant Leukemia cell lines
(University of Nairobi, 2019)Background: Cancer treatment failure is majorly attributed to the emergency of multi-drug resistance of cancer cells towards most conventional drugs used in chemotherapy hence the need for more active principles with less ...
