University of Nairobi Institutional Repository: Recent submissions
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Effect of Finishing Protocols and Staining Solutions on Color Stability of Dental Resin Composites
(University of Nairobi, 2022)Objective: The objective of this study was to evaluate the effect of finishing protocol and exposure to staining solutions on color stability of dental resin composites. Materials and methods: A nanofill and microhybrid ... -
Occurrence of serum antibodies to Toxoplasma gondii and associated risk factors in donkeys from central Kenya
(University of Nairobi, 2022-01)Toxoplasma gondii is an intracellular parasite of zoonotic concern and economic importance in humans and animals, respectively. This study was conducted to determine the occurrence of T. gondii and associated risk factors ... -
Demographic consequences of mutualism disruption: Browsing and big-headed ant invasion drive acacia population declines
(University of Nairobi, 2022-05)Across the globe, biological invasions have disrupted mutualisms, producing reverberating consequences for ecosystems. Although invasive species frequently trigger mutualism disruptions, few studies have quantified the ... -
Pairwise Joint Modeling of Clustered and High-dimensional Outcomes With Covariate Missingness in Pediatric Pneumonia Care
(University of Nairobi, 2022)Multiple outcomes reflecting different aspects of routine care are a common phenomenon in health care research. A common approach of handling such outcomes is multiple univariate analyses, an approach which does not allow ... -
Adolescent fertility and its determinants in Kenya: Evidence from Kenya demographic and health survey 2014
(University of Nairobi, 2022-01)Background: Adolescent fertility in Kenya is vital in the development and execution of reproductive health policies and programs. One of the specific objectives of the Kenyan Adolescent Sexual Reproductive Health (ASRH) ... -
Progress on the national action plan of Pakistan on antimicrobial resistance (AMR): a narrative review and the implications
(University of Nairobi, 2022-01)Introduction: The emergence of antimicrobial resistance (AMR) is a threat to public health. In 2015, the World Health Organization (WHO) introduced a global action plan to tackle AMR in the World Health Assembly. Pakistan's ... -
Effects of cytochrome P450 2B6 and constitutive androstane receptor genetic variation on Efavirenz plasma concentrations among HIV patients in Kenya
(University of Nairobi, 2022-03)The effects of genetic variation of cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) on efavirenz (EFV) plasma concentration was evaluated among 312 HIV patients in Nairobi Kenya. The EFV plasma ... -
Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya
(University of Nairobi, 2022-01)Background: Late-stage blinding sequalae of trachoma such as trachomatous trichiasis (TT) typically take decades to develop and often do so in the absence of ongoing ocular Chlamydia trachomatis infection. This suggests ... -
Pentavalent vaccination in Kenya: coverage and geographical accessibility to health facilities using data from a community demographic and health surveillance system in Kilifi County
(University of Nairobi, 2022-04)Background: There is substantial evidence that immunization is one of the most significant and cost-effective pillars of preventive and promotive health interventions. Effective childhood immunization coverage is thus ... -
High Level of Pre-Treatment HIV-1 Drug Resistance and Its Association with HLA Class I-Mediated Restriction in the Pumwani Sex Worker Cohort
(University of Nairobi, 2022-01)Background: We analyzed the prevalence of pre-antiretroviral therapy (ART) drug resistance mutations (DRMs) in a Kenyan population. We also examined whether host HLA class I genes influence the development of pre-ART ... -
Global article collection: essential reads from around the world
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Psychological Experiences of Caregivers of Adolescents Diagnosed With Substance Use Disorder Attending a Youth Centre in a Low-resource Setting
(University of Nairobi, 2022)Caregivers, whether a biological parent, adoptive parent, or a relative such as a grandparent, of adolescent with substance use disorder (SUD) undergo immense psychological and social strains, as they have to deal with ... -
CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study
(University of Nairobi, 2022-07)Background: Tuberculosis remains a leading cause of global mortality, especially for adults and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum-based assays are needed to improve tuberculosis ... -
In Vitro Anti-hiv and Cytotoxic Effects of Pure Compounds Isolated From Croton Macrostachyus Hochst. Ex Delile
(University of Nairobi, 2022)Croton macrostachyus is an important plant in traditional African medicine, widely utilized to treat a variety of diseases. In Kenya, HIV-infected patients use leaf and root decoctions of the plant as a cure for cough, ... -
Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate
(University of Nairobi, 2022-05)Depot medroxyprogesterone acetate (DMPA) is an injectable hormonal contraceptive used by millions of women worldwide. However, experimental studies have associated DMPA use with genital epithelial barrier disruption and ... -
Long-term Health Outcomes of Adolescent Character Strength Interventions: 3- to 4-year Outcomes of Three Randomized Controlled Trials of the Shamiri Program
(University of Nairobi, 2022)Background Adolescents in low- and middle-income countries in need of mental health care often do not receive it due to stigma, cost, and lack of mental health professionals. Culturally appropriate, brief, and low-cost ... -
Behavioral Responses of Pyrethroid Resistant and Susceptible Anopheles Gambiae Mosquitoes to Insecticide Treated Bed Net
(University of Nairobi, 2022)Background Long-lasting insecticidal nets are an effective tool in reducing malaria transmission. However, with increasing insecticide resistance little is known about how physiologically resistant malaria vectors behave ... -
Co-infection of Pigs With Taenia Solium Cysticercosis and Gastrointestinal Parasites in Eastern and Western Uganda
(University of Nairobi, 2021)A study was carried out in Kamuli and Hoima districts in Eastern and Western regions of Uganda to determine the Taenia solium porcine cysticercosis (PCC) and gastrointestinal (GI) parasites co-infection status in pigs. One ... -
Nutritional Quality of Four Novel Porridge Products Blended With Edible Cricket (Scapsipedus Icipe) Meal for Food
(University of Nairobi, 2022)Currently, no data exist on the utilization of the newly described cricket species (Scapsipedus icipe) meal as additive in food products, though they have high protein (57%) with 88% total digestibility as well as a variety ... -
Constituents of Croton Megalocarpus With Potential Anti-hiv Activity
(University of Nairobi, 2022)Reported herein is an anti-HIV monochlorinated compound, 1β-acetoxy-3β-chloro-5α,6α-dihydroxycrotocascarin L (1), of the rare crotofolane diterpenoid class. Compound 1, a suspected artifact of extraction, along with the ...