CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa
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Date
2009Author
Karita, Etienne
Ketter, Nzeera
Price, Matt A.
Kayitenkore, Kayitesi
Kaleebu, Pontiano
Nanvubya, Annet
Anzala, Omu
Jaoko, Walter
Mutua, Gaudensia
Ruzagira, Eugene
Mulenga, Joseph
Sanders, Eduard J.
Mwangome, Mary
Allen, Susan
Bwanika, Agnes
Bahemuka, Ubaldo
Awuondo, Ken
Omosa, Gloria
Farah, Bashir
Amornkul, Pauli
Birungi, Josephine
Yates, Sarah
Stoll-Johnson, Lisa
Gilmour, Jill
Stevens, Gwynn
Shutes, Erin
Manigart, Olivier
Hughes, Peter
Dally, Len
Scott, Janet
Stevens, Wendy
Fast, Pat
Kamali, Anatoli
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Clinical laboratory reference intervals have not been established in many African countries, and non-local
intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African participants. Using
laboratory reference intervals derived from other populations excludes potential trial volunteers in Africa and makes AE
assessment challenging. The objective of this study was to establish clinical laboratory reference intervals for 25 hematology,
immunology and biochemistry values among healthy African adults typical of those who might join a clinical trial
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- Faculty of Health Sciences (FHS) [10378]