Bacterial vaginosis in HIV-infected women induces reversible alterations in the cervical immune environment
Date
2008Author
Rebbapragada, Anuradha
Howe, Kathryn
Wachihi, Charles
Pettengell, Christopher
Sunderji, Sherzana
Huibner, Sanja
Ball, T. Blake
Plummer, Francis A.
Jaoko Walter G.
Kaul, Rupert
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Bacterial vaginosis (BV) has been associated with
increased HIV cervicovaginal shedding. We hypothesized that this might relate to BV-associated increases in mucosal activated CD4+ T cells, which could enhance local HIV replication BV induces significant and reversible alterations in cervical immune cell populations and local inflammatory cytokines
that would be expected to enhance local HIV replication
URI
http://www.ncbi.nlm.nih.gov/pubmed/18989228http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10119
Citation
J Acquir Immune Defic Syndr Volume 49, Number 5, December 15, 2008Subject
Altered vaginal flora,Bacterial vaginosis,
Genital tract,
HIV,
Inflammation,
Mucosal immunology,
Transmission
Collections
- Faculty of Health Sciences (FHS) [10377]