Antibacterial activities of erythromycins A, B, C, and 0 and some ,of their derivatives
Date
1985Author
Kibwage, IO
Hoogmartens, Jos
Roets, Eugene
Vanderhaeghe, Hubert
Verbist, Ludo
Dubost, Maurice
Pascal, Claude
Petitjean, Pierre
Levol, George
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The MICs of erythromycins A, B, C, and J) and some of their derivatives were determined against 21 gram-positive and 15 gram-negative microorganisms, Antibacterial activity was confined to gram-poSiti,'e and very few gram-negative bacter-ia. Erythromycin U was somewhat less active than er-ythromycin A, and erythromycin C and D showed about half thaI activity or even less. Most other dcrivuti ves had negligible activity. Determination of potency by diffusion and lurhidimclJ'ic assays were in line with MICs. The cxurninatiou of the results of these assays, howevcr , revealed that there are differences between the data of different laboranu-ics , depending on the microorganisms and conditions used
Citation
Antimicrobial agents and chemotherapy Nov 1985Collections
- Faculty of Health Sciences (FHS) [10214]