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    Antibacterial activities of erythromycins A, B, C, and 0 and some ,of their derivatives

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    1985 - Kibwage - Antibacterial activities of Erythromycins A, B, C and D and some of their derivatives.pdf (1.454Mb)
    Date
    1985
    Author
    Kibwage, IO
    Hoogmartens, Jos
    Roets, Eugene
    Vanderhaeghe, Hubert
    Verbist, Ludo
    Dubost, Maurice
    Pascal, Claude
    Petitjean, Pierre
    Levol, George
    Type
    Article
    Language
    en
    Metadata
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    Abstract
    The MICs of erythromycins A, B, C, and J) and some of their derivatives were determined against 21 gram-positive and 15 gram-negative microorganisms, Antibacterial activity was confined to gram-poSiti,'e and very few gram-negative bacter-ia. Erythromycin U was somewhat less active than er-ythromycin A, and erythromycin C and D showed about half thaI activity or even less. Most other dcrivuti ves had negligible activity. Determination of potency by diffusion and lurhidimclJ'ic assays were in line with MICs. The cxurninatiou of the results of these assays, howevcr , revealed that there are differences between the data of different laboranu-ics , depending on the microorganisms and conditions used
    URI
    http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10219
    Citation
    Antimicrobial agents and chemotherapy Nov 1985
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    • Faculty of Health Sciences (FHS) [10214]

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