Browsing Faculty of Science & Technology (FST) by Author "Derese, Solomon"

Now showing items 1-3 of 3

    • Antimalarial drug discovery through in silico scaffold hopping using a database of natural products of Kenya 

      Rogo, O. Michael; Oyim, James,; Manyim, S,; Ndakala, A lbert; Derese, Solomon (University of Nairobi, 2015)
      Despite the efforts to 'roll back malaria', statistics still shows that there are 97 countries and territories with ongoing malaria transmission, and 7 countries i n the prevention or ...

    • Rotenoid derivatives from Kenyan Millettia and Derris species as larvicidal agents 

      Yenesew, Abiy; Kiplagat, John T; Mushibe, Eluid K; Derese, Solomon; Midiwo, Jacob O; Kabaru, JM; Heydenreich, Matthias; Peter, Martin G (Department of Chemistry, University of NairobiDepartment of Zoology, University of Nairobi,, 2000)
      Rotenone (1), one of the most extensively used natural insecticides, was reported to be highly toxic to the 4th instar larvae of Aedes aegypti (Abe et al., 1985). The insecticidal activities of rotenone and some other ...

    • +)-tephrodin: a novel flavone with antiplasmodial activity from tephrosia purpurea 

      Muiva - Mutisya, Lois; Macharia, Bernard; Heydenreich, Matthias; Koch, Andreas; Akala, Hoseah M; Derese, Solomon; Omos, Leonidah K.; Yusuf, Amir O.; [et al.] (University of Nairobi, 2015)
      In our continued search for antiplasmodial agents with unique structures from Tephrosia species, the isolation, characterization and antiplasmodial activity of a novel flavone and three known flavonoids ...