Analysis of Co-trimoxazole products on the Kenyan market
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Date
1998Author
Kibwage, IO
Ondari, Clive O
Mureithi, Isaiah G
Thuranira, Joseph K
Hoogmartens, Jos
Type
ArticleLanguage
enMetadata
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The content of Sulphamethoxazole/Trimethoprim preparations were evaluated using the official British Pharmacopoeia method and a liquid chromatographic method. The two methods were shown to give similar performances and were used alternately. Twenty two tablet samples from 16 products were analysed of which 7 failed the requirements of content. Fifteen Co-trimoxazole suspension samples from 11 products were analysed of which 4 failed the content requirements. There were variations in chemical content amongst batches of same product. Failure rate amongst samples was 31 % for imported and 22% for locally manufactured tablets and 50% for imported and 11 % for locally manufactured suspensions
Citation
East and Central African journal of pharmaceutical sciences, vol. 1 no.2. 1998Collections
- Faculty of Health Sciences (FHS) [10377]