dc.contributor.author | Kamau, M. W. | |
dc.contributor.author | Chindia, M. L. | |
dc.contributor.author | Dimba, EA | |
dc.contributor.author | Awange, D. | |
dc.contributor.author | Gathece Loice W | |
dc.date.accessioned | 2013-02-20T12:00:14Z | |
dc.date.issued | 2011-02 | |
dc.identifier.citation | East African Medical Journal | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10462 | |
dc.description | Clinico-histopathologic types of maxillofacial malignancies with emphasis on sarcomas: a 10- year review | en |
dc.description.abstract | round: Sarcomas are malignant neoplasms that occur anywhere in the human body. Though their occurrence in the head and neck region is rare vis-a-vis other malignancies, their presence is of tremendous concern due to their often grave prognosis. Objective: To determine the pattern of occurrence, histopathologic types of maxillofacial sarcomas and their proportion to other malignant neoplasms of this region based on archival material accumulated over 10 years (2000-2009). Design: A combined retrospective and prospective cross-sectional study. Setting: The University of Nairobi Dental Hospital (UNDH).
Subjects: All caseswithadiagnosisofsarcomaregisteredbetween2000-2009wereevaluated. Results: Of the 528 malignancies recorded over the ten-year period, 427 (80.9%) were of epithelial origin while 101 (19.1 %) were sarcomas. Patients with epithelial malignancies were older (54.16 ± 15.94 years) than patients with sarcomas (31.73 ± 16.78) with the differences having been statistically significant. Osteosarcoma was the most commonly occurring sarcoma (29.7%), followed by Kaposi's sarcoma (KS) (28.7%), fibrosarcoma (FBS) (18.8%), and rhabdomyosarcoma (RMS) (9.9%). Sarcomas peaked in the third decade with 70% occurring below the age of 40 years. The maxilla and the mandible were the most afflicted sites in the maxillofacial region accounting' for 52%. The patients on average presented to medical personel about nine months after noticing the lesion with the most frequent complaint having been swelling.
Conclusion: The present study confirms the relative rarity of maxillofacial sarcomas. It also provides data on the histopathologic types and demographic characteristics of maxillofacial sarcomas in a select Kenyan population. This information is a contribution to the comprehensive documentation of sarcomas that occur globally and is useful in the provision of baseline data upon which future prospective analytical protocols may arise. | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | Vol. 88 No.2 February 2011; | |
dc.title | Clinico-Histopathologic types of Maxillofacial Malignancies with emphasis on sarcomas: | en |
dc.title.alternative | A 10- year review | en |
dc.type | Article | en |