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dc.contributor.authorOgeto, John O.
dc.contributor.authorMaitai, C.K
dc.date.accessioned2013-02-21T08:31:45Z
dc.date.issued1983
dc.identifier.citationEast African Medical Journal Vol.60 No.9 September 1983en
dc.identifier.urihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10570
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/6653467
dc.description.abstractThe mediciinal value of Strychnos henningsii plant. Particularly as an appetite stimulant has long been recognised by the indigenous people of Kenya even before this is properly documented in scientific literature The present work involves isolation and purification of the bitter alkaloidal principles present in powdered plant material. Quantitative estimation of the alkaloidal content, in each morphological part of the plant was done and the result compared with that of closely related species. Strychnos nux vomica, an officiall drug in several pharmacopoeia. Examination of the isolated alkaloidal was done using thin layer chromatography (TLC) and gas, liquid chromatography (GLC) to deter¬mine the number of alkaloids present in the plant. The median lethal du-e (I.D) in rats and the bitterness threshold in humans for the isolated alkaloidal rnixture were determined and compared with those reported for S, nux vomica. Result-, of this work indicate that S. henningsii can be substitute for S. nux vomica as an apettite stimulanten
dc.language.isoenen
dc.titleThe scientific basis for the use of strychnos henningsii(gilg) Plant material to stimulate appetiteen
dc.typeArticleen
local.publisherDepartment of pharmacy faculty of medicine,University of Nairobien


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