| dc.contributor.author | Achola, K.J. | |
| dc.contributor.author | Mwangi, J.W. | |
| dc.contributor.author | Munenge, R.W. | |
| dc.contributor.author | Mwaura, A.M. | |
| dc.date.accessioned | 2013-02-25T09:42:53Z | |
| dc.date.issued | 1996 | |
| dc.identifier.citation | International Journal of Pharmacognosy 1996, Vol. 34, No.2, pp. 141-144 | en |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/11138 | |
| dc.description.abstract | A 70% methanol aerial part extract of Vernonia glabra caused a fall in blood pressure in anaesthetised rats. After the 50 ug dose, systolic, diastolic, and mean blood pressures decreased by 56%, 66%, and 61% respectively below the baseline levels. The adrenaline-like activity of the extract was not antagonised by L( -) propranolol on isolat¬ed rabbit heart. The extract caused contraction on the isolated rabbit ileum and was abolished with atropine, suggesting the presence of a compound with acetylcholine-like activity. The extract on isolated guinea pig ileum caused contraction which was dose related | en |
| dc.language.iso | en | en |
| dc.title | Pharmacological activities of vernonia glabra | en |
| dc.type | Article | en |
| local.publisher | Department of Pharmacy, University of Nairobi, College of Health Sciences, | en |
