dc.contributor.author | Mbugua, M N | |
dc.contributor.author | Yusuf, A O | |
dc.contributor.author | Gitu, P M | |
dc.contributor.author | Bhat, B M | |
dc.date.accessioned | 2013-02-26T15:09:20Z | |
dc.date.issued | 2006 | |
dc.identifier.citation | Bull.Chem.Soc. Ethiop.2007, 21(1), 103-110 | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/11879 | |
dc.description.abstract | Vernonia oil obtained by Soxhlet extraction from the seeds of Vernonia
galamensis ssp. nairobensis was reacted with 2-aminopyridine, 2-(aminomethyl)pyridine and
2-(aminoethyl)pyridine using a 1:3 mole ratio of vernonia oil to amine at varied temperatures
to give the corresponding vernolamides. The expected vernolamide from the reaction of 2aminopyridine
and the oil was not formed. N-(2-pyridinylmethyl)vernolamide and N-(2pyridinylethyl)vernolamide
.exhibited antibacterial activity that was shown to be higher
against gram-positive (Bacillus subtiIis) than gram-negative (Escherichia colt) bacteria. The
vernolamides did not show any antifungal activity. | en |
dc.language.iso | en | en |
dc.publisher | Chemical Society of Ethiopia | en |
dc.subject | Vernonia galamensis | en |
dc.subject | 2-Aminopyridine | en |
dc.subject | N-(2-pyridinylmethyl)vernolamide | en |
dc.subject | N-(2-pyridinylethyl)vernolamide | en |
dc.subject | Antimicrobial activity | en |
dc.title | Conversion of vernonia galamensis oil to pyridinylvernolamides and their antimicrobial activities | en |
dc.type | Article | en |
local.publisher | Chemistry | en |