A experimental solanum incanum l. Poisoning in goats
Date
2010Author
Thaiyah, A G
Nyaga, P N
Maribei, J M
Mbuthia, P G
Ngatia, T A
Nduati, D
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
A study was carried out to determine the toxicity of unripe fruits of S. incanum L in goats. Dried unripe fruits of S. incanum L, were orally fed to goats at a dose rate of 0 (group1), 0.75 (group 2), 1.5 (group 3) and 2.25 (group 4) g/Kg /day for 9 weeks. Clinical signs were observed daily while blood with and without anticoagulant was taken weekly for haematological and biochemical analysis. Clinical signs started on day two with shivering. All group 4 goats (2.25g/ kg) showed bloat, colic, coughing and shivering while one goat had additional signs of depression, staggering gait and continuous bleating before death. One goat in group 3 (1.5g/kg) had bloat, shivering, progressive weakness, depression, staggering gait, lateral recumbency, leg paddling movements, continuous bleating and death while the rest were asymtomatic. All group 2 goats (0.75g/kg) were asymptomatic. Group 4 goats had hydroperitoneum and hydropericardium while group 3 had hydroperitoneum and fibrinous pericarditis. Group 2 goats had no significant pathology. On histopathology the brain of group 3 and 4 goats showed microthrombi, marked wallerian degeneration of neurons and necrosis of purkinje cells while group 2 goats only showed congestion. Other organs in the body also showed significant pathology. The results indicate that unripe fruits of S. incanum L are toxic to goats and allowing animals to graze on this plant could be deleterious to their health
Citation
Bull. Anim. Hlth. Prod. Afr., (2010), 58, 35-43.Publisher
Department of Veterinary Pathology, Microbiology and Parasitology Department of Clinical Studies Department of Public Health, Pharmacology and Toxicology Faculty of Vet Medicine
Subject
Poisonous plantsSolanum incanum
Solanaceae
cerebellar disease
diseases of goats
neuropathology