dc.contributor.author | Thaiyah, A G | |
dc.contributor.author | Nyaga, P N | |
dc.contributor.author | Maribei, J M | |
dc.contributor.author | Mbuthia, P G | |
dc.contributor.author | Ngatia, T A | |
dc.contributor.author | Nduati, D | |
dc.date.accessioned | 2013-03-15T11:48:23Z | |
dc.date.issued | 2010 | |
dc.identifier.citation | Bull. Anim. Hlth. Prod. Afr., (2010), 58, 35-43. | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/14118 | |
dc.description.abstract | A study was carried out to determine the toxicity of unripe fruits of S. incanum L in goats. Dried unripe fruits of S. incanum L, were orally fed to goats at a dose rate of 0 (group1), 0.75 (group 2), 1.5 (group 3) and 2.25 (group 4) g/Kg /day for 9 weeks. Clinical signs were observed daily while blood with and without anticoagulant was taken weekly for haematological and biochemical analysis. Clinical signs started on day two with shivering. All group 4 goats (2.25g/ kg) showed bloat, colic, coughing and shivering while one goat had additional signs of depression, staggering gait and continuous bleating before death. One goat in group 3 (1.5g/kg) had bloat, shivering, progressive weakness, depression, staggering gait, lateral recumbency, leg paddling movements, continuous bleating and death while the rest were asymtomatic. All group 2 goats (0.75g/kg) were asymptomatic. Group 4 goats had hydroperitoneum and hydropericardium while group 3 had hydroperitoneum and fibrinous pericarditis. Group 2 goats had no significant pathology. On histopathology the brain of group 3 and 4 goats showed microthrombi, marked wallerian degeneration of neurons and necrosis of purkinje cells while group 2 goats only showed congestion. Other organs in the body also showed significant pathology. The results indicate that unripe fruits of S. incanum L are toxic to goats and allowing animals to graze on this plant could be deleterious to their health | en |
dc.language.iso | en | en |
dc.subject | Poisonous plants | en |
dc.subject | Solanum incanum | en |
dc.subject | Solanaceae | en |
dc.subject | cerebellar disease | en |
dc.subject | diseases of goats | en |
dc.subject | neuropathology | en |
dc.title | A experimental solanum incanum l. Poisoning in goats | en |
dc.type | Article | en |
local.publisher | Department of Veterinary Pathology, Microbiology and Parasitology | en |
local.publisher | Department of Clinical Studies | en |
local.publisher | Department of Public Health, Pharmacology and Toxicology | en |
local.publisher | Faculty of Vet Medicine | en |