dc.contributor.author | McLean, ED | |
dc.contributor.author | Allen, LH | |
dc.contributor.author | Neumann, CG | |
dc.contributor.author | Peerson, JM | |
dc.contributor.author | Siekmann, JH | |
dc.contributor.author | Murphy, SP | |
dc.contributor.author | Bwibo, NO | |
dc.contributor.author | Demment, MW | |
dc.date.accessioned | 2013-04-15T10:01:17Z | |
dc.date.available | 2013-04-15T10:01:17Z | |
dc.date.issued | 2007 | |
dc.identifier.citation | J Nutr. 2007 Mar;137(3):676-82 | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/23964388 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/15975 | |
dc.description.abstract | The high prevalence of vitamin B-12 deficiency in many regions of the world is becoming recognized as a widespread public health problem, but it is not known to what extent this deficiency results from a low intake of the vitamin or from its malabsorption from food. In rural Kenya, where a previous study identified a high prevalence of inadequate vitamin B-12 intakes, this study examined whether plasma vitamin B-12 concentrations were associated with dietary sources of the vitamin at baseline and could be increased by supplementation with animal source foods (ASF). The 4 experimental groups in 503 school children were: 1) control (no food provided); 2) githeri (a maize and bean staple with added oil); 3) githeri + meat (githeri + minced beef); or 4) githeri + milk (githeri + milk). Feedings were isocaloric. Dietary data were collected at baseline, and biochemical data at baseline and after 1 and 2 y of feeding. Baseline plasma vitamin B-12 concentration was 193.6 +/- 105.3 pmol/L and correlated with % energy from ASF (r = 0.308, P < 0.001). The odds ratio for low plasma vitamin B-12 (<148 pmol/L), which occurred in 40% of children, was 6.28 [95% CI: 3.07-12.82] for the lowest vs. highest ASF intake tertile (P < 0.001). Feeding ASF (meat or milk) greatly reduced the prevalence of low plasma vitamin B-12 (P < 0.001). The high prevalence of low plasma vitamin B-12 concentrations in these children is predicted by a low intake of ASF, and supplemental ASF improves vitamin B-12 status | en |
dc.language.iso | en | en |
dc.title | Low plasma vitamin B-12 in Kenyan school children is highly prevalent and improved by supplemental animal source foods. | en |
dc.type | Article | en |
local.publisher | Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI, USA: | en |
local.publisher | ARS Western Human Nutrition Research Center, University of California, Davis, CA 95616 | en |
local.publisher | School of Public Health, University of California, Los Angeles, CA 90095 | en |
local.publisher | Global Livestock-CRSP, University of California, Davis, CA 95616 | en |
local.publisher | University of Nairobi, Nairobi, Kenya | en |