| dc.contributor.author | Odoyo, A. O. | |
| dc.contributor.author | Abuga, K. O. | |
| dc.contributor.author | Mugo, H. N. | |
| dc.contributor.author | Mang'oi, J. S | |
| dc.date.accessioned | 2022-10-05T12:58:32Z | |
| dc.date.available | 2022-10-05T12:58:32Z | |
| dc.date.issued | 2022-09-06 | |
| dc.identifier.citation | Odoyo, A. O., Abuga, K. O., Mugo, H. N., & Mang'oi, J. S. (2021). Quality of Metronidazole Benzoate Suspension Products Marketed in Nairobi County, Kenya. The East and Central African Journal of Pharmaceutical Sciences, 24(3), 131-135. | en_US |
| dc.identifier.uri | http://uonjournals.uonbi.ac.ke/ojs/index.php/ecajps/article/view/1102 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke/handle/11295/161406 | |
| dc.description.abstract | Metronidazole benzoate is an ester derivative of metronidazole utilized in the
formulation of oral suspensions owing to its palatability. The drug is liable to
hydrolytic degradation during shelf life which could lower assay values and increase
free metronidazole content. A medicine quality survey study was carried out in
Nairobi County whereby 32 metronidazole benzoate samples representing 13 brands
were collected from retail pharmacies. The samples were subjected to British
Pharmacopoeia specifications for pH, free metronidazole content and assay. From
the results obtained, only nine samples (28.1%) passed all the quality tests performed
while five (15.6%), seven (21.9%) and 18 (56.3%) did not comply with pH,
metronidazole content and assay specifications respectively. The results obtained
demonstrate the existence of substandard metronidazole benzoate products in the
market. This underscores the need for regular post market surveillance surveys and
execution of appropriate regulatory actions | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | East Cent. Afr. J. Pharm. Sci | en_US |
| dc.subject | Quality control, assay, metronidazole content, pH, substandard and falsified medicine, degradation | en_US |
| dc.title | Quality of metronidazole benzoate suspension products marketed in Nairobi County, Kenya | en_US |
| dc.type | Article | en_US |
