dc.contributor.author | Gachara, Nicholas K | |
dc.date.accessioned | 2022-12-02T10:43:03Z | |
dc.date.available | 2022-12-02T10:43:03Z | |
dc.date.issued | 2022 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke/handle/11295/161931 | |
dc.description.abstract | Background: Oncologic Esophagectomy is a cornerstone in the management of resectable esophageal cancer, with postoperative anastomotic leaks a common complication. Few studies have looked specifically at the mortality and morbidity associated with cervical esophagogastric anastomotic leaks as a complication of oncologic esophagectomy.
Study Objective: To describe the incidence and early outcomes of cervical esophago-gastric anastomotic leak among patients undergoing oncologic esophagectomy at Kenyatta National Hospital.
Methodology: A 7 year retrospective cohort study of 205 patients who underwent oncologic esophagectomy, with a cervical esophago-gastric anastomosis at KNH between January 2014 and December 2021was performed. Data was collected via consecutive sampling of all patients who underwent oncologic esophagectomy;of particular interest was whether they developed an anastomotic leak and its associated complications such as mortality, length of hospital stay, time to oral intake and need for surgical intervention.
Results : Out of 205 patients who underwent esophagectomy, 41 developed CEGAL giving an incidence of 20% with only 12%(n=5 ) requiring surgical intervention. The overall mortality rate was 5.85%(n=12 ). There was an association between presence of CEGAL and length of hospital stay (p<0.0001) and delayed resumption of oral feeding (p<0.0001). However there was no association between CEGAL and increased risk of mortality (p=0.118).
Conclusion: The presence of CEGAL increases length of hospital stay and the duration to resumption of oral feeds, with no significant effect on hospital mortality. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Nairobi | en_US |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
dc.title | The Incidence and Early Outcomes of Cervical Esophagogastric Anastomotic Leaks Following Oncologic Esophagectomy at Kenyatta National Hospital | en_US |
dc.type | Thesis | en_US |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |