Chloroquine Resistance: Proposed Mechanisms and Countermeasures

dc.contributor.author	Guantai, Eric M.
dc.contributor.author	Chibale, Kelly
dc.date.accessioned	2013-04-22T13:55:56Z
dc.date.available	2013-04-22T13:55:56Z
dc.date.issued	2010-10
dc.identifier.citation	Current Drug Delivery	en
dc.identifier.uri	http://www.ingentaconnect.com/content/ben/cdd/2010/00000007/00000004/art00006
dc.identifier.uri	http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16516
dc.description.abstract	Malaria has been, and remains, one of the biggest global health concerns as far as infectious diseases are concerned, with yearly incidence and mortality figures running into millions. One of the major drawbacks to the control of this disease has been the emergence of drug resistant strains of the causative agent, which limits the successful use of many clinically available antimalarial drugs. This review discusses chloroquine resistance; it highlights some of the proposed molecular mechanisms of chloroquine resistance, but dwells more on efforts at reversing chloroquine resistance and the concept of chloroquine resistance-reversal agents	en
dc.language.iso	en	en
dc.relation.ispartofseries	Vol. 7, Number 4, 2010 , pp. 312-323(12);
dc.title	Chloroquine Resistance: Proposed Mechanisms and Countermeasures	en
dc.type	Article	en