Herpes simplex virus type 2 infection among young uncircumcised men in Kisumu, Kenya
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Date
2008Author
Mehta, S.D
Moses, S
Agot, K
Agingu, W
Parker, C
Ndinya-Achola JO.
Bailey, R.C
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
OBJECTIVES:
To identify factors associated with herpes simplex virus type 2 (HSV-2) infection among men aged 18-24 in Kisumu, Kenya.
METHODS:
Baseline data from a randomised trial of male circumcision were analysed. Participants were interviewed for sociodemographic and behavioural risks. The outcome was HSV-2 by antibody status. Risk factors were considered singly and in combination through logistic regression models.
RESULTS:
Among 2771 uncircumcised men, 766 (27.6%; 95% confidence interval (CI) 26.0% to 29.3%) tested antibody positive for HSV-2. The median age at first sex was 16 years, and the median number of lifetime sexual partners was four. HSV-2 seroprevalence increased from 19% among 18-year-olds to 43% among 24-year-olds (p<0.001). In multivariable analysis, statistically significant risks for infection were increasing age (adjusted odds ratio (AOR) = 1.22-2.58), being married or having a live-in female partner (AOR = 1.80; 95% CI 1.28 to 2.53), preferring "dry" sex (AOR = 1.39; 95% CI 1.14 to 1.69), reported penile cuts or abrasions during sex (AOR = 1.58; 95% CI 1.32 to 1.91), increasing lifetime sex partners (multiple response categories; AORs ranging from 1.65 to 1.97), and non-student occupation (multiple response categories; AORs ranging from 1.44 to 1.93). Risk decreased with reported condom used at last sex (AOR = 0.82; 95% CI 0.68 to 0.99).
CONCLUSION:
Primary prevention efforts should be initiated at an early age. The same behavioural interventions used currently for HIV prevention-abstinence, reducing the number of sex partners and increasing condom use-should be effective for HSV-2 prevention
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/17855489http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16607
Citation
Sex Transm Infect. 2008 Feb;84(1):42-8. Epub 2007 Sep 12Publisher
Department of Epidemiology and Biostatistics, University of Illinois Chicago School of Public Health, Illinois, USA
Collections
- Faculty of Health Sciences (FHS) [10377]