dc.contributor.author | Agot, KE | |
dc.contributor.author | Ndinya-Achola Jeckoniah O. | |
dc.contributor.author | Kreiss, JK | |
dc.contributor.author | Weiss, NS | |
dc.date.accessioned | 2013-04-25T06:38:33Z | |
dc.date.available | 2013-04-25T06:38:33Z | |
dc.date.issued | 2004 | |
dc.identifier.citation | Epidemiology. 2004 Mar;15(2):157-63 | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/15127907 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16661 | |
dc.description.abstract | BACKGROUND:
Most studies that have found an association between uncircumcised status and infection with human immunodeficiency virus type 1 (HIV-1) have compared participants from various demographic backgrounds, among which the prevalence of other risk factors might have varied. We report findings from a study conducted among men within a single ethnic community in which circumcision was dictated by the religious denomination to which the men belonged.
METHODS:
Of the 1217 eligible men, we included in the analysis 845 who gave blood samples for HIV-1 testing and who were confirmed as either fully circumcised (n = 398) or uncircumcised (n = 447). The seroprevalence of HIV-1 was compared between the 2 groups.
RESULTS:
All correlates of HIV-1 prevalence that we measured were distributed similarly between circumcised and uncircumcised men. The seroprevalence of HIV-1 was 30% among the uncircumcised men and 20% among the circumcised men. Among uncircumcised men, HIV-1 seroprevalence was similar between men from circumcising denominations (31%; n = 111) and noncircumcising denominations (30%; n = 336). The crude prevalence ratio for HIV infection associated with not being circumcised was 1.5 (95% confidence interval = 1.2-2.0); and adjustment for other measured risk factors for HIV-1 infection had little impact on this result.
CONCLUSION:
Our study provides evidence that circumcision is associated with a reduced risk of HIV-1 infection | en |
dc.language.iso | en | en |
dc.title | Risk of HIV-1 in rural Kenya: a comparison of circumcised and uncircumcised men | en |
dc.type | Article | en |
local.publisher | Department of Epidemiology, University of Washington, Seattle, Washington, USA | en |
local.publisher | Department of Medical Microbiology, University of Nairobi | en |