dc.contributor.author | Katz, M. A. | |
dc.contributor.author | Lebo, E. | |
dc.contributor.author | Emukule, G. | |
dc.contributor.author | Njuguna, H. N. | |
dc.contributor.author | Aura, B. | |
dc.contributor.author | Cosmas, L. | |
dc.contributor.author | Audi, A. | |
dc.contributor.author | Junghae, M. | |
dc.contributor.author | Waiboci, Lillian Wangechi | |
dc.contributor.author | Olack, B. | |
dc.contributor.author | Bigogo, G. | |
dc.contributor.author | Njenga, M.K. | |
dc.contributor.author | Feikin, D. R. | |
dc.contributor.author | Breiman, R. F. | |
dc.date.accessioned | 2013-04-25T06:43:30Z | |
dc.date.available | 2013-04-25T06:43:30Z | |
dc.date.issued | 2012-12 | |
dc.identifier.citation | J. infect Dis. | en |
dc.identifier.uri | http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/23169973 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16663 | |
dc.description.abstract | BACKGROUND:
The epidemiology and burden of influenza remain poorly defined in sub-Saharan Africa. Since 2005, the Kenya Medical Research Institute and Centers for Disease Control and Prevention-Kenya have conducted population-based infectious disease surveillance in Kibera, an urban informal settlement in Nairobi, and in Lwak, a rural community in western Kenya.
METHODS:
Nasopharyngeal and oropharyngeal swab specimens were obtained from patients who attended the study clinic and had acute lower respiratory tract (LRT) illness. Specimens were tested for influenza virus by real-time reverse-transcription polymerase chain reaction. We adjusted the incidence of influenza-associated acute LRT illness to account for patients with acute LRT illness who attended the clinic but were not sampled.
RESULTS:
From March 2007 through February 2010, 4140 cases of acute LRT illness were evaluated in Kibera, and specimens were collected from 1197 (27%); 319 (27%) were positive for influenza virus. In Lwak, there were 6733 cases of acute LRT illness, and specimens were collected from 1641 (24%); 359 (22%) were positive for influenza virus. The crude and adjusted rates of medically attended influenza-associated acute LRT illness were 6.9 and 13.6 cases per 1000 person-years, respectively, in Kibera, and 5.6 and 23.0 cases per 1000 person-years, respectively, in Lwak. In both sites, rates of influenza-associated acute LRT illness were highest among children <2 years old and lowest among adults ≥50 years old.
CONCLUSION:
In Kenya, the incidence of influenza-associated acute LRT illness was high in both rural and urban settings, particularly among the most vulnerable age groups | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | Vol. 15;206 Suppl 1:S53-60( 2012); | |
dc.title | Epidemiology, seasonality, and burden of influenza and influenza-like illness in urban and rural Kenya, 2007-2010. | en |
dc.type | Article | en |
local.publisher | Department of Medicine. College of Health Sciences. University of Nairobi | en |