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dc.contributor.authorMagro, CM
dc.contributor.authorCrowson, AN
dc.contributor.authorAlfa, M
dc.contributor.authorNath, A
dc.contributor.authorRonald, A
dc.contributor.authorNdinya-Achola, JO
dc.contributor.authorNasio, J
dc.date.accessioned2013-04-25T13:35:55Z
dc.date.available2013-04-25T13:35:55Z
dc.date.issued1996
dc.identifier.citationHum Pathol. 1996 Oct;27(10):1066-70en
dc.identifier.urihttp://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/8892592
dc.identifier.urihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16853
dc.description.abstractChancroid, the most common cause of genital ulceration in Africa, is known to be associated epidemiologically with heterosexual transmission of human immunodeficiency virus (HIV). The pathophysiological mechanisms by which chancroid might facilitate the spread of HIV are obscure. To investigate the role of chancroid in HIV transmission, the authors studied the histological features of biopsies from 11 men with penile chancroid lesions including five who were serologically positive for HIV. The histomorphologic and immunophenotypic nature of the inflammatory infiltrates suggests that there is a significant role for cell-mediated immunity in the host response to Hemophilus ducreyi infection. This response may be critical to the role of chancroid in HIV transmissionen
dc.language.isoenen
dc.titleA morphological study of penile chancroid lesions in human immunodeficiency virus (HIV)-positive and -negative African men with a hypothesis concerning the role of chancroid in HIV transmissionen
dc.typeArticleen
local.publisherDepartment of Pathology, Beth Israel Hospital, Harvard Medical School, Boston, MA, USAen
local.publisherDepartment of Medical Microbiology, University of Nairobi, Kenya, Africaen


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