Impact of maternal HIV infection on obstetrical and early neonatal outcome.
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Date
1990Author
Braddick, MR
Kreiss, JK
Embree, JB
Datta, P
Ndinya-Achola, JO
Pamba, H
Maitha, G
Roberts, PL
Quinn, TC
Holmes, KK
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
In a case-control study of 177 HIV-seropositive and 326 seronegative women and their newborns in Nairobi, Kenya, maternal HIV infection at term was independently associated with travel to other African countries [odds ratio (OR) 4.9, P less than 0.0001], history of a blood transfusion since 1980 (OR 3.5, P = 0.01), history of more than one sexual partner in the previous 5 years (OR 1.8, P = 0.02) and unmarried status (OR 1.8, P = 0.02). Neonates of HIV-positive and HIV-negative women differed little with respect to occurrence of congenital malformations, stillbirths, in-hospital mortality, sex, APGAR score, or gestational age. However, the mean birth weight of singleton neonates of HIV-positive women was significantly lower than that of controls (3090 versus 3220 g, P = 0.005), and birth weight was less than 2500 g in 9% of cases and 3% of controls (OR 3.0, P = 0.007). Among neonates of HIV-seropositive women, birth weight was less than 2500 g in 17% if mothers were symptomatic and 6% if mothers were asymptomatic (OR 3.4, P = 0.08)
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/2261113http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17001
Citation
AIDS. 1990 Oct;4(10):1001-5.Publisher
Department of Medical Microbiology, University of Nairobi, Kenya
Collections
- Faculty of Health Sciences (FHS) [10377]