The importance of core groups in the epidemiology and control of HIV-1 infection

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Date
1991Author
Plummer, FA
Nagelkerke, NJ
Moses, S
Ndinya-Achola, JO
Bwayo, JJ
Ngugi, Elizabeth N
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
In Africa, HIV transmission occurs mainly through heterosexual intercourse. High-frequency transmitter core groups are key to the epidemiology of HIV-1 and STD on the continent. The rapid growth of the HIV-1 epidemic in Africa appears to have resulted, in part, from social and economic factors which result in individuals' frequent engagement in sexual intercourse with members of HIV-infected core groups. Understanding the importance of core groups in HIV-1 transmission is therefore key to developing more effective programs for the control of HIV-1. Sections explore the core groups concept and the sexual transmission of infection, social and economic forces creating core groups in Africa, the interaction of STD and HIV-1 in core groups, the effect of STD on HIV-1 disease progression in core groups in accelerating the HIV-1 epidemic, the role of core group interventions in control programs, balancing disease control with the potential for victimization, and research needs
URI
http://www.ncbi.nlm.nih.gov/pubmed/1669915http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17030
Citation
AIDS. 1991;5 Suppl 1:S169-76Publisher
Department of Medical Microbiology, University of Nairobi, Kenya
Collections
- Faculty of Health Sciences (FHS) [10227]