Infection and disease after perinatal exposure to Chlamydia trachomatis in Nairobi, Kenya
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Date
1988Author
Datta, P
Laga, M
Plummer, FA
Ndinya-Achola, JO
Piot, P
Maitha, G
Ronald, AR
Brunham, RC
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
A cohort of 49 infants exposed to maternal chlamydial infection and 40 nonexposed infants was studied after birth for a mean of 3.3 +/- 1.5 and 3 +/- 1.7 mo, respectively. Eighteen (37%) exposed infants had at least one positive culture for Chlamydia trachomatis, whereas C. trachomatis was not isolated from any of the nonexposed infants. Eighteen (37%) exposed infants developed ophthalmia neonatorum (n = 12) or infant conjunctivitis (n = 7), compared with six (15%) of the nonexposed infants (P = .04). Six (12%) exposed infants developed pneumonia, compared with none of the 40 nonexposed infants (P = .05). One infant in the exposed group died during follow-up. These results suggest that appreciable infant morbidity in Kenya may be associated with the high prevalence of maternal chlamydial infection
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/3411148http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17102
Citation
J Infect Dis. 1988 Sep;158(3):524-8Publisher
Department of Medical Microbiology, University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10377]