Correlation between cytology and thyroid function test
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Date
2006Author
Sang, CK
Kigondu, CS
Muchiri, L
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
BACKGROUND:
Thyroid dysfunction can be evaluated by measuring serum thyroid stimulating hormone (TSH), total tri-iodothyronine (T3) and total thyroxine (T4) which will establish euthyroidism, hyperthyroidism and hypothyroidism. Fine needle aspiration (FNA) is the diagnostic test of choice in determining whether a nodule is benign or malignant.
OBJECTIVE:
To correlate hormonal levels to FNA cytologic findings.
DESIGN:
A cross-sectional study.
SETTING:
Kenyatta National Hospital (KNH).
RESULTS:
Forty two patients had their thyroid profiles done and the results were correlated with FNA diagnosis. Majority of patients had nodular goiter (83.3%), of which 47.6% had euthyroidism, 16.7% had biochemical euthyroidism, 11.9% had hyperthyroidism, 4.8% had sub-clinical hyperthyroidism and 2.4% had sub-clinical hypothyroidism. Three patients (7.1%) with FNA diagnosis of non-diagnostic sample had euthyroidism while 2.4% each with papillary carcinoma, thyroglossal cyst, and atypia, had a hormonal profile of euthyroidism. There was no significant statistical difference (p > 0.05) of the mean levels of T4 (0.406), T3 (0.311), and TSH (0.90), between and within the various groups of FNA cytological diagnoses.
CONCLUSION:
The study showed that there was no correlation between T4, T3, and TSH easurements and FNA cytological diagnoses
URI
http://www.ncbi.nlm.nih.gov/pubmed/17310678http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17204
Citation
East Afr Med J. 2006 Oct;83(10):533-8Publisher
Department of Dental Health, School of Medicine, Moi University, Department of Pathology, University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10387]