Chemical studies on the roots of Uvaria welwitschii.
dc.contributor.author | Moriyasu, M, | |
dc.contributor.author | Nakatani, N | |
dc.contributor.author | Ichimaru, M | |
dc.contributor.author | Nishiyama, Y | |
dc.contributor.author | Kato, A, | |
dc.contributor.author | Mathenge, S.G | |
dc.contributor.author | Juma, F.D | |
dc.contributor.author | Chalo Mutiso, P.B | |
dc.date.accessioned | 2013-04-27T10:47:38Z | |
dc.date.available | 2013-04-27T10:47:38Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | J Nat Med. 2011 Apr;65(2):313-21. | en |
dc.identifier.uri | http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/21234693 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17375 | |
dc.description.abstract | A chemical investigation of the chloroform extract of the roots of Uvaria welwitschii (Annonaceae), an African traditional medicine taken for stomach ache, led to the isolation of eight new compounds, named welwitschins A-H (1-8), together with five known compounds (9-13). The structural elucidation by spectroscopic studies of the compounds isolated is described. All new compounds were flavonoids having a 2-hydroxy-3,4,6-trimethoxyphenyl moiety in the A-ring, and unsubstituted phenyl in the B-ring. Four of them (1-4) were monomeric flavonoids while the others (5-8) were dimeric flavonoids. The cytotoxicity of the isolated compounds against human promyelocytic leukemia HL-60 cells was investigated. | en |
dc.language.iso | en | en |
dc.title | Chemical studies on the roots of Uvaria welwitschii. | en |
dc.type | Article | en |
Files in this item
This item appears in the following Collection(s)
-
Faculty of Health Sciences (FHS) [10387]