Cytotoxic C-benzylated dihydrochalcones from Uvaria acuminata
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Date
2004Author
Ichimaru, M
Nakatani, N
Takahashi, T
Nishiyama, Y,
Moriyasu, M
Kato, A,
Mathenge, S.G
Juma, FD
Nganga, JN
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Two new C-benzylated dihydrochalcones, isochamuvaritin (1) and acumitin (2), have been isolated from the African medicinal plant Uvaria acuminata, together with the previously reported benzylbenzoate (3), uvaretin (4), isouvaretin (5), diuvaretin (6), and uvangoletin (7). The structural elucidation of compounds 1 and 2 in spectroscopic studies is described. C-Benzylated dihydrochalcones, especially 1, 2, 4, and 6, showed considerable cytotoxicity toward human promyelocytic leukemia HL-60 cells.
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/14709883http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17383
Citation
Chem Pharm Bull (Tokyo). 2004 Jan;52(1):138-41.Collections
- Faculty of Health Sciences (FHS) [10377]