dc.contributor.author | Pinner, RW | |
dc.contributor.author | Onyango, F | |
dc.contributor.author | Perkins, BA | |
dc.contributor.author | Mirza, NB | |
dc.contributor.author | Ngacha, DM | |
dc.contributor.author | Reeves, M | |
dc.contributor.author | DeWitt, W | |
dc.contributor.author | Njeru, E | |
dc.contributor.author | Agata, NN | |
dc.contributor.author | Broome, CV | |
dc.date.accessioned | 2013-04-29T10:41:55Z | |
dc.date.available | 2013-04-29T10:41:55Z | |
dc.date.issued | 1992 | |
dc.identifier.citation | J Infect Dis. 1992 Aug;166(2):359-64 | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/1634807 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17637 | |
dc.description.abstract | An epidemic of meningococcal disease occurred in Nairobi, Kenya, during 1989, outside the "meningitis belt" of sub-Saharan Africa. About 3800 cases occurred between April and November (250/100,000 population). The case-fatality rate was 9.4% among hospitalized patients. Areas that included Nairobi's largest slums had particularly high attack rates. The epidemic displayed an unusual age distribution, with high attack rates among those 20-29 years old. A vaccination campaign was conducted. By early January, the weekly case count had fallen to 25 from a high of 272 (in September). A case-control study estimated the vaccine efficacy to be 87% (95% confidence interval, 67%-95%). A model estimated that the vaccination campaign reduced the number of cases by at least 20%. Multilocus enzyme electrophoretic typing demonstrated that the strain responsible for this large epidemic is closely related to strains that caused other recent epidemics, documenting further spread of what may be a particularly virulent clonal complex of group A Neisseria meningitidis | en |
dc.language.iso | en | en |
dc.title | Epidemic meningococcal disease in Nairobi, Kenya, 1989. The Kenya/Centers for Disease Control (CDC) Meningitis Study Group | en |
dc.type | Article | en |
local.publisher | Division of Bacterial and Mycotic Diseases, Centers for Disease Control, Atlanta, GA 30333 | en |