Metabolism of cathinone to d-norpseudoephedrine in humans.
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Date
1983Author
Guantai Anastacia N.
Maitai, CK
Type
ArticleLanguage
enMetadata
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Cathinone, a potent psychostimulant isolated from young shoots of Catha edulis was given to four human volunteers. Examination of urine collected from the volunteers at predetermined intervals showed the presence of unchanged cathinone, d-norpseudoephedrine, and two unidentified basic substances. The observed biotransformation of cathinone to the less potent psychostimulant, d-norpseudoephedrine involves reduction of a ketone group to alcohol, a common metabolic pathway in humans.
URI
http://www.ncbi.nlm.nih.gov/pubmed/6644577http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17736
http://www.ncbi.nlm.nih.gov/pubmed/6644577
Citation
J Pharm Sci. 1983 Oct;72(10):1217-8Collections
- Faculty of Health Sciences (FHS) [10378]