Infection with Trichomonas vaginalis increases the risk of HIV-1 acquisition
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Date
2007Author
Ndinya-Achola, JO
Mandaliya, K
Jaoko Walter G.
Type
ArticleLanguage
enMetadata
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We conducted a prospective study among women in Mombasa, Kenya, to determine whether Trichomonas vaginalis infection was associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) infection. At monthly follow-up visits, laboratory screening for HIV-1 and genital tract infections was conducted. Among 1335 HIV-1-seronegative women monitored for a median of 566 days, there were 806 incident T. vaginalis infections (23.6/100 person-years), and 265 women seroconverted to HIV-1 (7.7/100 person-years). Trichomoniasis was associated with a 1.52-fold (95% confidence interval, 1.04-2.24-fold) increased risk of HIV-1 acquisition after adjustment for potential confounding factors. Treatment and prevention of T. vaginalis infection could reduce HIV-1 risk in women.
URI
http://www.ncbi.nlm.nih.gov/pubmed/17262712http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24340
Citation
J Infect Dis. 2007 Mar 1;195(5):698-702. Epub 2007 Jan 22Collections
- Faculty of Health Sciences (FHS) [10387]