An investigation of a traditional herbal therapy used to treat malaria in Kisii
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Date
2003Author
Bosire, Kefa Ogonyo
Type
ThesisLanguage
enMetadata
Show full item recordAbstract
The plant Rhamnus prinoides L. Herit (Rhamnaceae) IS used in
traditional medicine for the treatment of malaria among other diseases
by the Kisii community. By using column chromatographic methods,
geshoidin was isolated and tentatively identified. Other isolates were also
obtained but were not identified.
Allextracts were found to have in vitro antimalarial activity. The highest
activitywas in the hexane and dichloromethane extracts with ICso values
of 19.9 /lgjml and 30.3 /lgjml,respectively. None of the extracts showed
toxicityin the brine shrimp test.
This study provides scientific basis for the use of the plant part in the
treatment ofmalaria by the herbalist in Kisii
Citation
M. Pharmacy (pharmaceutical Analysis)Sponsorhip
University of NairobiPublisher
Department of Pharmacy, University of Nairobi
Description
Master of Pharmacy