dc.contributor.author | Cege, Esther N | |
dc.date.accessioned | 2013-05-23T13:29:10Z | |
dc.date.available | 2013-05-23T13:29:10Z | |
dc.date.issued | 1991 | |
dc.identifier.citation | Degree Of Master of Medicine in Anaesthesia | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/24952 | |
dc.description | This dissertation is submitted in part fulfilment
for the requirements of the Degree
Of Master of Medicine in Anaesthesia of
the University Of Nairobi,1991. | en |
dc.description.abstract | Vecuronium bromide in a standard dose of O.lmg per
kilogram body weight was used on one hundred patients
of the American Society of Anaesthesiologists status
I and II undergoing abdominal or limb surgery. The
time of onset of action with each intravenous dose of
vecuronium and its duration of action time were measured
The pulse rate and blood pressure were monitored before
and after administration of vecuronium.
Informed verbal consent was obtained from each patient.
The premedication, induction, maintenance and reversal
drugs were standardized. A nerve stimulator on the ulnar
nerve was used to obtain onset of maximal block and time
of at least 75% recovery from the block. An automatic
electronic blood pressure machine model DS.91 was
used to monitor the pulse rate and blood pressure
at the necessary intervals.
It was found that the average onset time
of action of vecuronium O.lmg/kg was 194
seconds (3 minutes 14 seconds). The average
duration of action time was 29.55 minutes.
A decline in pulse rate and mean arterial
pressure was noted after the induction
of anaesthesia. This was not found to
be clinically significant. Intraoperatively ,
from time of injection of vecuronium to
twenty minutes later. there was minimal
change in pulse rate and mean arterial
pressure. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | A study of the neuromuscular blocking properties and cardiovascular effects of vecuronium | en |
dc.type | Thesis | en |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |
local.publisher | School of Medicine | en |