Serum Vitamin E And The Sickling Status In Children With Sickle Cell Anaemia As Seen At Kenyatta National Hospital
Abstract
In this study, serum vitamin E levels were determined
among 62 children with sickle cell anaemia and 35 age- ,
matched controls. Among the sicklers, the irreversibly
sickled cell counts were done and correlated with the
serum vitamin E levels.
There was a significant difference in serum vitamin E
values (P < 0.001). the sickle cell anaemia patients
showing tendency to deflciency with 27% of them deficient
as against 2.9% of the controls.
It was found that the vitamin E deficient sicklers had
a significantly higher irreversibly sickled cell counts
(P < 0002), indicating that vitamin E is en important
inhibitor of the irreversibly sickled cell formation.
URI
http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/25010http://www.ncbi.nlm.nih.gov/pubmed/2282895
Citation
Masters of Medicine (Paediatrics and Child Health)Publisher
University of Nairobi School of Medicine