Neutrophil phagocytic function in uncomplicated diabetes mellitus patients of African origin as seen at Kenyatta National Hospital
Abstract
This was a comparative study carried out over a six months period with an aim
of determining the neutrophil phagocytic function in uncomplicated diabetes
mellitus patients and in non-diabetic patients (control group) as seen at Kenyatta
National Hospital. A total of 80 subjects were studied. Of these 40 were
diabetics (cases) and 40 were controls (non-diabetics). Of the 40 diabetics, 26
were males and 14 were females. The cases were matched with the controls sex,
and age ± 3 years.
The result showed that there was a significant impairment in the neutrophil
phagocytic function in the diabetics compared with the non diabetics.
Comparatively more neutrophils from non diabetics ingested yeasts than
neutrophils from diabetics. There was a higher number of neutrophils that
ingested a given number of yeasts when the controls and cases were compared.
There was no significant linear correlation between the phagocytic function and
the glycaemic control as measured by glycosylated hemoglobin
Citation
Master of Medicine (internal Medicine), University of Nairobi 2004Publisher
University of Nairobi, School of Medicine