A comparative study of needle aspiration biopsy with histology in the diagnosis of enlarged prostate

Abstract

Forty one patients with enlarged prostate were studied as regards their acid phospatase estimation, clinical findings on rectal examination and needle aspiration biopsy. The results of this study were compared with histological diagnosis after surgery. It was found that combined needle aspiration biopsy, rectal examination plus acid phosphatase estimation gave a reliable diagnosis of pathological state of prostate gland in terms of malignancy in 82 per cent of the cases. Since the disease in consideration is early cancer, the combined diagnostic approach as above can be quite useful in contemplating early surgery to eradicate early cancer with hope of cure. On the other hand, those who believe in hormonal therapy and want to avoid operation can start the hormonal treatment quite early.