Prevalence of helicobacter pylori in chronic renal failure patients with dyspepsia
Abstract
Background:The aim of the study was to determine the prevalence of H.
pylori in dyspeptic patients with chronic renal failure.
Methods: One hundred and fifty four patients with dyspepsia, in two groups
of seventy-seven patients each were studied. The patients were divided on
the basis of presence or absence of CRF. H. pylori was tested for using the
biopsyurease test and histology. Patients were considered to have H. pylori
if theytested positive on both tests.
Results: The prevalence of H. pylori in CRF was 53.2%. There was no
statistically significant difference between the prevalence of H. pylori in
CRF patients from that observed in the controls. Patients with
endoscopicallyproven PUD had a very high prevalence of H. pylori (87.30/0)
regardlessof their renal function.
Conclusion: Dyspepsia in patients with or without CRF is due to multiple
causes and just over 500/0 is attributable to H. pylori. The prevalence of H.
pylori in dyspeptic CRF patients is similar to that in dyspeptic patients with
normal renal function. We recommend that all patients with dyspesia should
routinely undergo endoscopy and H. pylori studies before treatment for the
dyspepsiais started.
Citation
Degree of Master of Medicine (Internal Medicine)Publisher
University of Nairobi School of Medicine
Description
A dissertation submitted in partial fulfillment
for the Degree of Master of Medicine (Internal
Medicine) in the University of Nairobi