dc.contributor.author | Waweru, Wairimu | |
dc.date.accessioned | 2013-05-25T09:37:47Z | |
dc.date.available | 2013-05-25T09:37:47Z | |
dc.date.issued | 1991 | |
dc.identifier.citation | Masters of Medicine (Pathology) | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/25640 | |
dc.description.abstract | A total of 407 cases were recorded under "ovarian lesions" in
the department of histopathology KNH over a 5 year period,
extending from 1st January 1986 to December 1990. These 407
case excluded all the lesions recorded as inflammatory .
Out of ~07 recorded cases, 368 cases had either the previous
histology slides retrieved or had the paraffin embedded tissue
blocks retrieved and processed.
Following a microscopic review of the 368 cases, 70 of these
were omitted because they did not show any ovarian tissue or
the required diagnosis as outlined.
Two hundred and ninety eight cases we re the re fore recruited
into the study Sixty percent of these were diagnosed as
normal ovaries or their variances, that is corpora lutea and
graafian follicles that were apparently considered abnormal
ovaries and hence removed. Eight of this had no epithelial
lining and were diagnosed as simple ovarian cysts.
Forty percent of the cases were microscopically identified as
neoplasm that are listed in the World Health Organization (WHO)
classification namely epithelial tumours , germ cell tumours
sex cord-stromal tumours and lymphoma
Three of these neoplastic cases had two types of tumours
identified, this included two cases with diagnoses of Brenner
tumour with mucinous cystadenoma and another case with a
diagnosis of benign cystic teratoma and serous cystadenoma. In
two of the above cases, the tissues demonstrating the two types
of tumour, were submitted in separate bottles.
The diagnoses of all the cases were independently made without
prior knowledge of the original diagnoses. The second diagnoses
were first made by the investigator and then reviewed by the
supervisor before the final diagnoses were made. The second
diagnoses were then compared with the original ones made by
various pathologists within the department of human pathology
on staff at the time when the tissues were submitted to the
laboratory.
Out of the slides examined 66% were found to be of reasonable
technical quality, adequate for a definitive diagnosis. The
remaining 34% were of a less than the desired quality and
required an increased amount of time to achieve a diagnosis.
There was an overall diagnostic interobserver variation of 21% | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | Review and diagnosis of normal ovaries, their variances and neoplastic lesions. Evaluation of the technical quality of the slides and interobserver diagnostic concurrences | en |
dc.type | Thesis | en |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |
local.publisher | School of Medicine | en |