Agenesis of the corpus callosum with associated inter-hemispheric cyst and right frontal pachygyria presenting with psychiatric symptoms in a Kenyan Citation:

Abstract

This case report presents a 26 year old man who had a history of childhood onset seizures, mild cognitive slowing and social withdrawal. He gradually developed symptoms of depression and attempted suicide once. He presented to the authors following a recurrence of his seizures. On examination they noted a normal general and neurological examination apart from some frontal lobe signs on mental status examination. He also had features of psychosis and labile mood. On CT brain scan he had agenesis of the corpus callosum (CC) with associated interhemispheric cyst and right frontal pachygyria. The authors suggest that clinicians in developing countries should be alert to organic disorders presenting with psychiatric symptoms.