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dc.contributor.authorMostad S B, S B
dc.contributor.authorKreiss, J K
dc.contributor.authorRyncarz, A J
dc.contributor.authorOverbaugh, J
dc.contributor.authorMandaliya, K
dc.contributor.authorChohan, B
dc.contributor.authorNdinya-Achola, JO
dc.contributor.authorBwayo, JJ
dc.contributor.authorCorey, L
dc.date.accessioned2013-05-31T07:02:02Z
dc.date.available2013-05-31T07:02:02Z
dc.date.issued1999
dc.identifier.citationMostad Sb, Kreiss Jk, Ryncarz Aj, Overbaugh J, Mandaliya K, Chohan B, Ndinya-achola J, Bwayo Jj, Corey L.cervical Shedding Of Cytomegalovirus In Human Immunodeficiency Virus Type 1-infected Women.j Med Virol. 1999 Dec;59(4):469-73., O., Prof. Ndinya-achola J. , J Med Virol. 1999 Dec;59(4):469-73., (1999)en
dc.identifier.uriHttp://profiles.uonbi.ac.ke/jndinya/publications/mostad-sb-kreiss-jk-ryncarz-aj-overbaugh-j-mandaliya-k-chohan-b-ndinya-achola-j
dc.identifier.urihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/28050
dc.description.abstractCervical shedding of cytomegalovirus (CMV) is important in transmission of CMV to exposed sexual partners and neonates. We evaluated prevalence and correlates of CMV DNA shedding in cervical secretions from a large cohort of HIV-1-seropositive women. Using polymerase chain reaction (PCR) assays, CMV DNA was detected in 183 (59%) cervical swab samples from 311 women. Cervical shedding of CMV DNA was significantly associated with shedding of HIV-1 DNA (odds ratio 1.8; 95% confidence interval 1.1-2.8). CMV shedding was also more frequent in women with Neisseria gonorrhoeae and Trichomonas vaginalis infections, but these associations were not statistically significant. Cervical shedding of CMV in HIV-1-infected women is very frequent and may reflect higher risk of transmission to sexual partners and neonates than previously appreciated.en
dc.language.isoenen
dc.publisherUniversity of Nairobien
dc.titleCervical Shedding Of Cytomegalovirus In Human Immunodeficiency Virus Type 1-infected Women.en
dc.typeArticleen
local.publisherSchool of Public Health Centre for HIV Prevention and Researchen


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