dc.contributor.author | Muthuri, Joel J | |
dc.date.accessioned | 2013-06-03T14:21:26Z | |
dc.date.available | 2013-06-03T14:21:26Z | |
dc.date.issued | 1981 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/28800 | |
dc.description.abstract | This is a prospective study done over a period of six
months to evaluate some clinical and immunological aspects of
childhood asthma. 104 asthmatic children and a control group
of 40 children between 2 and 10 years were looked at.
75% of the patients were below 5 years of age. No
sex ratio difference was noticed below 5 years of age but
there were twice as many girls as boys above this age.
63.5% of all the asthmatic children had their disease starting
before 2 years of age. 97.1% of the patients had their attacks
during cold wet season and these started at night. Expiratory
rhonchi was the commonest clinical sign found.
8.6% of the patients had active eczema and 31.7% gave
history suggestive of infantile eczema in the past. There was
history of asthma in a first degree relative in 45 (43.3%)
patientse77{74%) patients had their first supplementary
feed of artificial milk formulae introduced below the age.of
three months.
There was no significant difference in parasite
infestation rate between the asthmatic children and a
control group of non-asthmatic children.
54% of the patients had eosinophilia of more than
400 cells/dl in their peripheral blood compared to none
in the control group, and this had no relationship with the
parasitic infestation.
The asthmatics had significantly more positive skin reaction
to house-dust mites of Dermatophagoides species comp~red to the
non-asthmatics; multiple skin reactions were common.
No significant differences were found in immunoglobulin
IgA, IgG and IgM concentrations between the asthmatics and
the control group. However the IgG and IgM levels in the
control group were higher than has been found in caucasian
children in the Western World. | en |
dc.language.iso | en | en |
dc.title | Childhood Asthma: A Look At Some Clinical And Immunological Aspects | en |
dc.type | Thesis | en |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |