Hiv Type 1 Subtypes In Circulation In Northern Kenya.
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Date
2005Author
Khamadi, S A
Ochieng, W
Lihana, R W
Kinyua, J
Muriuki, J
Mwangi, J
Lwembe, R
Kiptoo, M
Osman, S,
Lagat, N
Pelle, R
Muigai, A
Carter, J Y
Oishi, I
Ichimura, H
Mwaniki, D L
Okoth, F. A
Mpoke, S
Songok, E M
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Kenya Medical Research Institute, Nairobi, Kenya. skhamadi@nairobi.mimcom.net The genetic subtypes of HIV-1 circulating in northern Kenya have not been characterized. Here we report the partial sequencing and analysis of samples collected in the years 2003 and 2004 from 72 HIV-1-positive patients in northern Kenya, which borders Ethiopia, Somalia, and Sudan. From the analysis of partial env sequences, it was determined that 50% were subtype A, 39% subtype C, and 11% subtype D. This shows that in the northern border region of Kenya subtypes A and C are the dominant HIV-1 subtypes in circulation. Ethiopia is dominated mainly by HIV-1 subtype C, which incidentally is the dominant subtype in the town of Moyale, which borders Ethiopia. These results show that cross-border movements play an important role in the circulation of subtypes in Northern Kenya.
URI
Http://profiles.uonbi.ac.ke/jcmwangi/publications/khamadi-sa-ochieng-w-lihana-rw-kinyua-j-muriuki-j-mwangi-j-lwembe-r-kiptoo-m-ohttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/29725
http://www.ncbi.nlm.nih.gov/pubmed/1621880
Citation
Khamadi Sa, Ochieng W, Lihana Rw, Kinyua J, Muriuki J, Mwangi J, Lwembe R, Kiptoo M, Osman S, Lagat N, Pelle R, Muigai A, Carter Jy, Oishi I, Ichimura H, Mwaniki Dl, Okoth Fa, Mpoke S, Songok Em. Hiv Type 1 Subtypes In Circulation In Northern Kenya., Cege, Dr. Mwangi Joseph , Aids Res Hum Retroviruses. 2005 Sep;21(9):810-4., (2005)Publisher
University of Nairobi School of Public Health Centre for HIV Prevention and Research
Collections
- Faculty of Health Sciences (FHS) [10377]