HPV 18 and cervical adenocarcinomas
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Date
1991-02Author
Bjersing, L
Evander, M
Gerdes, U
Stendahl, U
Wadell, G
Rogo, Khama O
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Using Southern blot or in situ hybridization, several studies have recently reported an association between HPV 18 and adenocarcinoma of the uterine cervix. In this study PCR was used to analyse the presence of HPV 16 and 18 in paraffin embedded biopsies of cervical adenocarcinoma in Northern Sweden. HPV DNA was confirmed in 11 (42%) of 26 cases. Seven (27%) were positive for HPV 18 and 4 (15%) for HPV 16. Nine of 13 premenopausal cases were HPV positive compared to only 2 of 13 postmenopausal cases (p less than 0.015). There was also a tendency towards previous negative cytology in HPV 18 positive premenopausal patients. The significance of these findings in relation to epidemiology of cervical adenocarcinoma is discussed
URI
http://www.ncbi.nlm.nih.gov/pubmed/1850213http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/29763
Citation
Anticancer Res. 1991 Jan-Feb;11(1):123-7Publisher
University of Nairobi. Department of Obstetrics and Gynaecology
Collections
- Faculty of Health Sciences (FHS) [10377]