Bone marrow examination at a paediatric hospital in Kenya.
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Date
2001-07Author
Dave P.
Githang'a Jessie N.
Type
ArticleLanguage
enMetadata
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OBJECTIVE: To investigate the main indications for, and common conditions found in bone marrow examinations (BME) of children. METHODS: This was a retrospective study from September 1, 1993 to September 3 1998. All bone marrow aspirate and trephine biopsy results were retrieved. The clinical data provided by clinicians were also noted. RESULTS: A total of 97 BME were recorded from patients aged two months to 13 years. The peak ages for BME were six to eight years (24% of patients). The more frequent indications for BME were unexplained anaemia found in 26% request forms, investigation for solid tumours (10%) and lymphoma (10%) and remission assessment after treatment for leukaemia (26%). The main findings were malignancy (27%) with leukaemia being commonest (ALL) 16% of patients and acute myeloblastic leukaemia (5%). Haematinic deficiency was seen in 12.7% of cases with iron deficiency being the commonest. There were some notable differences and similarities in the study as compared to a similar one performed at a local referral hospital. CONCLUSION: The importance of BME as a crucial investigational tool in the management of patients is underscored. Interpretation is more meaningful when the haematologist has adequate clinical data.
URI
Http://profiles.uonbi.ac.ke/jessiegithanga/publications/githanga-jn-dave-p-bone-marrow-examination-paediatric-hospital-kenya-eashttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/29902
http://www.ncbi.nlm.nih.gov/pubmed/11957247
Citation
Githang'a J N, Dave P. Bone Marrow Examination At A Paediatric Hospital In Kenya. East Afr Med J. 2001 Jul;78(7 Suppl)Publisher
University of Nairobi Department of Human Panthology
Collections
- Faculty of Health Sciences (FHS) [10377]