Four-country surveillance of intestinal intussusception and diarrhoea in children
View/ Open
Date
2009-03Author
Awasthi, S
Agarwal, G G
Mishra, V
Nag, V L
El, Sayed H F
da, Cunha A J
Madeiro, A
Jain, D
Macharia, W M
Ndung'u, J
Awasthi, S
Wakhlu, A
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
AIM:
Establishment of baseline epidemiology of intussusception in developing countries has become a necessity with the possibility of reintroduction of rotavirus vaccine. The current study assessed the seasonal trend in cases admitted with intussusceptions and dehydrating acute watery diarrhoea in children aged 2 months to 10 years.
METHODS:
In a prospective surveillance study, teaching and research hospital sites in India (Lucknow and Nagpur), Brazil (Fortazela), Egypt (Ismailia) and Kenya (Nairobi) established a surveillance where a network of hospitals with surgical facilities catered to a reference population of about 1-2 million for reporting of intussusception. One large hospital per site also recruited admitted cases of acute watery diarrhoea.
RESULTS:
From April 2004 to March 2006, 173 and 2346 cases of intussusception and diarrhoea, respectively, were recruited. Cases of intussusception had no apparent seasonality. Most cases of intussusception (61.3%) (107/173) were in the < or =1 year age group, with males comprising 68.8% (119/173) of all cases. Hospital mortality of intussusception was 4.2% (4/96). Cases of diarrhoea peaked in March, with 56.6% (1328/2346) of admitted cases being males. Majority (83.1%) of cases of diarrhoea had received antibiotics, and the hospital mortality was 0.8% (18/2280).
CONCLUSION:
Intussusception in the four participating countries exhibited no seasonal trend. We found that it is feasible to establish a surveillance network for intussusception in developing countries. Future efforts must define population base before the introduction of rotavirus vaccine and continue for some years thereafter
URI
http://www.ncbi.nlm.nih.gov/pubmed/19210606http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30078
Citation
J Paediatr Child Health. 2009 Mar;45(3):82-6.Publisher
University of Nairobi. Department of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, Kenya
Collections
- Faculty of Health Sciences (FHS) [10377]