dc.contributor.author | De Cock, K.M | |
dc.contributor.author | Awadh, S | |
dc.contributor.author | Raja, R. S | |
dc.contributor.author | Wankya, B. M | |
dc.contributor.author | Jupp, R. A | |
dc.contributor.author | Slavin, B | |
dc.contributor.author | Arap Siongok, T. K | |
dc.contributor.author | Rees, P. H | |
dc.contributor.author | Bertrand, J | |
dc.contributor.author | Lucas, S. B | |
dc.date.accessioned | 2013-06-10T07:02:27Z | |
dc.date.available | 2013-06-10T07:02:27Z | |
dc.date.issued | 1987 | |
dc.identifier.citation | Trans R Soc Trop Med Hyg. 1987;81(1):107-10. | en |
dc.identifier.uri | http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/3127951 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30399 | |
dc.description.abstract | Eighty-five patients with chronic splenomegaly and proven oesophageal varices were studied at Kenyatta National Hospital, Nairobi. The major defined groups were hepatosplenic schistosomiasis (24%), cirrhosis (20%) and portal vein occlusion (11%). Hyper-reactive malarial splenomegaly (tropical splenomegaly syndrome) was considered as the cause of oesophageal varices in only one patient. In 26% of cases liver biopsy was non-diagnostic and the extrahepatic portal vein was demonstrated radiologically to be patent. Such patients were thought to be suffering from idiopathic portal hypertension, not previously described elsewhere in Africa. Hepatitis B surface antigen was detected in 12% of controls and in 58% of patients with cirrhosis (p less than 0.001). Some serological marker of previous hepatitis B virus infection was present in 92% of patients with cirrhosis and in 79% of controls. Kamba patients from Machakos and Kitui Districts were significantly more prevalent than expected among these 85 cases of portal hypertension. | en |
dc.language.iso | en | en |
dc.title | Chronic splenomegaly in Nairobi, Kenya. II. Portal hypertension | en |
dc.type | Article | en |