| dc.contributor.author | Richardson, BA | |
| dc.contributor.author | John-Stewart, GC | |
| dc.contributor.author | Hughes, JP | |
| dc.contributor.author | Nduati, RW | |
| dc.contributor.author | Mbori-Ngacha, DA | |
| dc.contributor.author | Overbaugh, J | |
| dc.contributor.author | Kreiss, JK | |
| dc.date.accessioned | 2013-06-10T07:15:44Z | |
| dc.date.available | 2013-06-10T07:15:44Z | |
| dc.date.issued | 2003-03 | |
| dc.identifier.citation | J Infect Dis. 2003 Mar 1;187(5):736-40. Epub 2003 Feb 12. | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/12599046 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30416 | |
| dc.description.abstract | Human immunodeficiency virus type 1 (HIV-1) is transmitted through blood, genital secretions, and breast milk. The probability of heterosexual transmission of HIV-1 per sex act is.0003-.0015, but little is known regarding the risk of transmission per breast-milk exposure. We evaluated the probability of breast-milk transmission of HIV-1 per liter of breast milk ingested and per day of breast-feeding in a study of children born to HIV-1-infected mothers. The probability of breast-milk transmission of HIV-1 was.00064 per liter ingested and.00028 per day of breast-feeding. Breast-milk infectivity was significantly higher for mothers with more-advanced disease, as measured by prenatal HIV-1 RNA plasma levels and CD4 cell counts. The probability of HIV-1 infection per liter of breast milk ingested by an infant is similar in magnitude to the probability of heterosexual transmission of HIV-1 per unprotected sex act in adults. | en |
| dc.language.iso | en | en |
| dc.publisher | University of Nairobi. | en |
| dc.title | Breast-milk infectivity in human immunodeficiency virus type 1-infected mothers. | en |
| dc.type | Article | en |
| local.publisher | Department of Paediatrics and Child Health, Univeristy of Nairobi, Kenya | en |
