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dc.contributor.authorWangai, J
dc.contributor.authorThairu, K
dc.contributor.authorBharaj, BS
dc.contributor.authorTelang, BV
dc.date.accessioned2013-06-10T08:26:16Z
dc.date.available2013-06-10T08:26:16Z
dc.date.issued1982
dc.identifier.citationActa Physiol Acad Sci Hung. 1982;60(1-2):83-8.en
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/7184308
dc.identifier.urihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30481
dc.description.abstractThree fractions were isolated from the venom of Dendroaspis angusticeps by column chromatography on CM-Sephadex C-25. All the three fractions were shown to possess acetylcholinesterase inhibiting activity. The toxicity of the fractions as tested on mice were variable. Although the toxic signs were identical, fraction DaVI was highly lethal (LD50 1.9 microgram/g) whereas fractions DaIV and T39 were less lethal, the LD50 being 3.6 micrograms/g and 4.1 micrograms/g respectively. The three fractions significantly inhibited true acetylcholinesterase to the extent of 91-95%.en
dc.language.isoenen
dc.publisherUniversity of Nairobien
dc.titleIdentification and isolation of three acetylcholinesterase inactivating fractions in the venom of Dendroaspis angusticeps.en
dc.typeArticleen
local.publisherCollege of Health Sciencesen


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